Tuesday, March 8, 2011

is heart disease reversable?

Is heart disease reversible?

Now there is a question that will elicit strong opinions in the medical community especially among cardiologists whose specialty is to care for people with heart disease.
The textbook definition of heart disease or more specifically coronary artery atherosclerosis describes it as a progressive disease be treated but not cured.
Some authors have described a steady progression of the disease, however more careful analysis reveals that while coronary atherosclerosis starts when we are young its progression is a not steadily progressive but goes through active and quiescent phases.

Most cardiologists and other Physicians will insist that heart disease cannot be reversed. Some will focus totally on cholesterol levels and insist that taking a cholesterol lowering drug is all that is needed and won’t discuss it further.
Surely the goal of treating coronary disease would be to reduce and eliminate the plaque and indeed a huge amount of money has been spent attempting to demonstrate that cholesterol lowering drugs would cause the plaques to shrink.
Pfizer who makes the cholesterol lowering drug lipitor spent over one billion dollars developing and testing a drug that would raise the levels of the so called “good cholesterol”, HDL only to find that not only did they not reduce the amount of plaque but the patients had significant side effects and the drug was withdrawn from further research, in fact this and other events has led Pfizer to completely abandon further development of any heart related drugs.
A large multi center trial called REVERSAL, REVERSing Atherosclerosis with Aggressive Lipid lowering (the drug marketing department loves these acronyms) showed that while one dosage of one particular medication did seem to stop the growth of the plaque the other medication did not, so there was no reversal in spite of the considerable amount of media coverage and marketing that followed promoting the medication (Lipitor) which supposedly had a better result.
All of this data has been discouraging in stopping the largest single cause of death in the developed world.
On the other hand one can find easily on the Internet advertisements for a variety of books and products claiming to reverse heart disease.
Dr. Dean of Ornish has made a career of claiming that following his very strict no fat diet. The joke about the Ornish diet because if it is so strict is that “it won’t make you live longer it just seems like it”. My older brother many years ago went to in Ornish seminar in came back with a very simple interpretation of the diet, he said” if you put something in your mouth and it tastes good spit it out” Other authors have also insisted that eliminating all fat will stop and reverse heart disease. A large group of people believe that chelation therapy works however there has never been any data demonstrating its effectiveness at reducing plaque.

If all this seems discouraging do not give up hope there are a small group of us who believe and have some evidence that heart disease actually can be reversed to some extent.

We must remember that fundamentally coronary artery disease is not a cholesterol problem and the focus on cholesterol will not lead us to a solution. The fundamental cause of coronary artery disease is inflammation.
The idea that inflammation is the cause of coronary disease begin to emerge in the medical literature in the mid nineties. Interestingly enough the renewed attention on the cause of coronary disease came about because of the problem of re-stenosis after an angioplasty or a stent.

This research caused a fundamental reevaluation of our whole idea of coronary disease, once described is a bland lipid storage disorder. The new research by many scientists has now fully described the role of inflammation from the inception of the plaque when it is called a fatty streak, to its growth and eventual rupture with disastrous consequences such as heart attack or stroke.

We will discuss inflammation more fully in week four and help you understand this very complicated subject.
But for now let’s just talk about inflammation in its simplest forms, we have all experienced acute inflammation for example if we experience a cut or abrasion on our skin we will see that classic signs of inflammation that have been described for centuries.
Warmth (calor)
Pain (dolor)
Redness (rubor)
Swelling (tumor)

We now know if that this is exactly what’s going on inside of our coronary arteries and the rest of our arteries for that matter. We can’t see it we can’t feel it but we know that this is what is going on.
I have seen it thousands of times in the operating room and came to the conclusion that inflammation was involved even though the experimental work was just beginning. I certainly will not take credit because I did not have the skills or the facility to accomplish the work that ultimately proved the clinical observation.

Lets it go back to your skin abrasion and remember that over a short period of time the signs of inflammation including the swelling and redness go away, the body is built to heal itself. However if you continue to injure that same spot every day it will never heal.

Dr. Peter Libby from Harvard University has a written eloquently both in the medical literature and in such publications as Nature and Scientific American explaining the change in our fundamental knowledge of heart disease and explaining the mechanisms by which inflammation causes the plaque to form grow and eventually rupture. Although he is certainly brilliant and very influential I am always disappointed to see that his only solution for inflammation is to prescribe a statin medication.

CAN HEART DIESAE BE REVERED?

The answer is yes, but not if we continue the same approach of trying to find a spot in the inflammatory pathway to block the inflammatory response.
But this is the typical approach; we don’t really ask what the fundamental cause is? We only ask how can we produce a drug that blocks the inflammatory process and make monstrous amounts of money using this medication.

Inflammation is the normal response our body makes to injury.

So to reverse heart disease a two pronged approach that; 1) avoids injury, to do this we must understand what it is that injures our arteries on a daily basis so that we can avoid the injury. 2) Understand the inflammatory process and the natural, normal things that modulate the responses so that we can maximize this affect without any side effects as are common with most medications.



It seems to me and to some others that if we stopped the injury that was causing the inflammation we would stop the growth of the plaque and facilitate healing.

I do not have any hard data but I do have several observations of patients who had dramatic reduction in the amount of plaque in their arteries by following a program to reduce inflammation.
(We may want to insert a couple of testimonials here from the inflammation awareness site)
One in particular is a man in his early fifties who was treated by a cardiologist friend of mine for chest pains, he underwent a cardiac catheterization demonstrating 60 to 70 percent narrowing in all three coronary arteries, and he was prescribed the usual statin medications but was not satisfied and sought my advice. My advice to him was to begin taking an omega three supplement, vitamin D and to restrict the amount of sugar and simple carbohydrates in his diet; he was also instructed to begin walking 30 minutes daily. At his six month follow-up his cardiologist scheduled another cardiac catheterization and warned am to be ready to have several stents placed in the arteries. Much to the cardiologist surprise the narrowing were now reduced to 40%.
I know anecdotes are not data and do not prove anything, but the observation has objective measurement of reduction in plaque which has been impossible with our current medications to reduce cholesterol.
The approach here was to have this gentleman stop injuries to his arteries by consuming a diet which he was genetically adapted to eat, avoiding those things that we know cause inflammation in the arteries. This diet and the exercise he began to do caused his weight dropped almost 20 pounds significantly reducing the inflammatory cytokines produced by that fat. We then took a look at those things lacking in his diet that are known to modulate the inflammatory response namely omega 3 fatty acids from fish oil and adequate amounts of vitamin D both of which are well documented to modulate the inflammatory spots in blood vessels.

Dr. William Davis has collected data using CT scans of the heart to obtain what is called a calcium score. Calcium in the coronary arteries proves that there is plaque there.
Dr. Davis published a paper which I was privileged to review before its publication showing that in 63 patients using a program to reduce inflammation a significant number had a reduction in calcium score. He actually had trouble getting it published in some journals because this was the first time such a thing had been reported.

Clinical observations and a small number of patients demonstrating reversal of coronary disease can never get the attention that a huge randomized trial, but we will continue to make the observations and publicize the fact that coronary artery disease is reversible by controlling inflammation.

The fundamentals of reversing heart disease then are;
Reducing the number of injuries to our blood vessels
Naturally modulating the inflammatory response.

48 comments:

Anonymous said...

Nice to hear that you think plaques are reversible - I've been taking vitamin and mineral supplements since my MI & PCI last year and am feeling much better, especially since taking flaxseed oil twice a day and making sure my omega 3 to 6 ratio is a good 2:1. I stopped taking statins after 8 weeks because of the side effects - poor memory/concentration, aggresion, muscle aches. That got me reading about the cholesterol myth and vitamins and more recently the importance of good dietary fats/oils. I used to trust medicines and doctors but now realise that trust was undeserved - it's all about money. Research the internet and you will find masses of information about natural cures for many different health problems, most of which can be addressed by changing lifestyle and supplementing and taking a little exercise.

john and sapana said...

Dr. Baxter Montgomery is a cardiologist who has helped many patients reverse heart disease through nutrition. Some examples of his success stories are here, here and here. He also writes about it in his book. As for those who think it is torture to change to a plant-based diet, there are some awesome recipes out there for entrees, desserts, snacks, smoothies, etc. Many people who never thought they could eat such a diet are happy after making the change, especially when their health is dramatically better as a result. In my opinion we should eat to live, not live to eat.

Lyn said...

I would love to see more blog posts from you. This is a very important topic and I'd like to write something about it on my blog after I figure out what, exactly, we are supposed to be eating to 'fix' the inflammation in our systems.

Hodad said...

saw your note from a cool friend in the medical biz, right on, go against 'them' they need to . well go away my humble site since 2005

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Hodad said...

Hola, to the previous poster, I can help you, interesting to see if this doctor, after all these years all this greed is sincere,

we have the ability to cure ourselves,
I did my Mom until, the evil system in Myrtle Beach just overwhelmed me, ask me
all about what you eat, your environment and your attitude
as a surfer for 49 years well I am blessed and lucky, to have had great folks and access to good education and started traveling at an early age, NOT about the money folks too many work work work, make that money then hope that money will help them when they get older, it does NOT work like that
the medical system in amerika is a sad sick joke, prevention is the key and the cure, start with organic apple cider vinegar and turmeric and walnuts as a start
but then I move to El Salvador, in 19984 #1 reason MY health is more important than money back soon, not soon enough taking an ambulance down driving for my little fishing villages in Guatemala and El Salvador and Honduras to use, see you there maybe where a coconut water a day or so is best as this Dr. said, eat those saturated fats, but always walk, or swim


MagicalSpain.com - Private VIP tours in Spain + Portugal said...

Thank you Doctor! We¡d love to read more of your wisdom here on regaining health after we have been ripped off by Big Pharma & their lap dogs at the FDA.

Your point about losing 10% of body wieght is good. BUT suggest you clarify that as losing 10% body fat.

IF not most people crash diet and lose healthy muscle mass = lose metabolic power.

Doctor, we'd love to invite you to speak at a conference. Feel free to contact us for more fat loss & fitness help here => www.MetabolicMotivation.com

Healthcare India said...
This comment has been removed by the author.
Unknown said...

Yes disease is reversible and disease is preventable. The human body which is composed of trillions of cells is losing billions of cells and replacing billions of cells. In 1932 Dr Otto Warburg won the Nobel Prize for science in cell respiration.His research proved with proper oxygen, nutrients and elimination of toxins and acids,blood cells could live forever. More information is avalible at http://www.health4boomers.info

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Unknown said...

Since 2011, there has been remarkable progress in the diagnosis and treatment of the very thing Dr. Lundell alerts us - cardiac inflammation caused by SOFT PLAQUE. If there were a simple means of determining the degree of endothelial damage, predictability of a sudden cardiac event (ACS) would go up exponentially. More than 50% of heart attacks occur in individuals with one or NO risk factors with little or NO warning!

That means of diagnostic predictability now exists. The presence of "Hot" plaque and likelihood of Acute Coronary Syndrome in next five years is measurable via the PULS Cardiac Test (www.pulstest.com).

The PULS CARDIAC TEST was developed over years of clinical research. That research identified a battery of identical protein biomarkers using three statistical models with M.E.S.A.

The PULS Cardiac Test is THE new screening tool for helping to eliminate the dreaded "Widowmaker" - a sudden cardiac event resulting in death. This blood test will provide a significant motivational tool for caregivers and patients, as well as increase quality referrals to cardiologists where more aggressive interventions are required.

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Lea Paige Matteo said...

Chemicals used in industries gives me Leukemia Cancer and it's all started when I wanted to get off my job to get another job that when I got diagnose, at that very point I was so scared to die because it has infected my blood cells also I was prescribed drugs like Cyclophosphamide,Busulfan,Bosutinib,Cytarabine, Cytosar-U (Cytarabine),Dasatinib in all that was just to keep me waiting for my dying day. I got inspired by what I read from a lady called Tara Omar on blog spot on how Dr Itua cure her HIV/Aids then they were lettered below that says he can cure Cancer so I pick his contact on the testimony she wrote then I emailed Dr Itua hopefully he replied swiftly to my mail then I purchased his Herbal medicine also it was shipped to me here in Texas, I went to pick it at post office so he instructs me on how the treatment will take me three weeks to cure my Leukemia Disease, Joyfully I was cured by this Dr Itua Herbal Medicine.
I will advise you too to give a try to Dr Itua Herbal Medicine with the following diseases that he can help you cure forever___Diabetes, Herpes,HIV/Aids, Bladder Cancer, Breast Cancer, Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Scoliosis,Fibromyalgia,Fluoroquinolone Toxicity
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Dementia.Vaginal Cancer, Kidney Cancer, Lung Cancer, Skin Cancer, Uterine Cancer, Prostate Cancer, Colo_Rectal Cancer, Leukemia Cancer, Hepatitis, Brain Tumors, Tach Disease,Love Spell, Infertility, Hpv. GoodLuck,XoXo****
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vantaiconthoi.vn - Vận tải Con thoi said...

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